Data collected for SWEET

The SWEET Core Data pdf

Item

Request

number of centre

centrally assigned by SWEET

name of centre

 

location of centre

 

date of profil

day/month/year, this first profile date must include the earliest date of visit

last_data_upload

assigned by the team of Prof. Reinhard Holl

Expected patients type1

number of patients treated in the centre

Expected patients type2

 

Expected patients type3

 

Laboratory method of hba1c

1 = HPLC, 2 = DCA 2000, 3 = others

unithba1c

% or mmol/mol

mean of the normal HbA1c

 

SD of the normal HbA1c

 

Range of the normal HbA1C

 

last update on 11.11.2014

The SWEET Dataset pdf

Item

Request

Comment

Patient ID

only one ID per patient

 

sex

m/f

 

date of birth

month and year

if possible also day of birth

date of onset

month and year

if possible also day of onset

type of diabetes

1, 2, 3, 4

 

if type of diabetes = 3

subtype if known, accordant to ISPAD, see table below: diabetes subtypes

 

date of visit

day, month, year

 

height

cm

1 decimal

weight

kilogram

1 decimal

blood pressure systolic

mmHG

no decimal

blood pressure diastolic

mmHG

no decimal

HbA1c

mmol/mol or in %

1 or 2 decimals

cholesterol

mmol, mg/dl, mg/l

0-2 decimal

HDL cholesterol

mmol, mg/dl, mg/l

0-2 decimal

LDL cholesterol

mmol, mg/dl, mg/l

0-2 decimal

Triglyceride

mmol, mg/dl, mg/l

0-2 decimal

TSH

different unites possible

1-2 decimal

free T4

different unites possible

1-2 decimal

thyroid peroxidase antibody

different unites possible

1-2 decimal

antithyroglobulin antibody

different unites possible

1-2 decimal

celiac antibodies

values  or screened y/n and if screened normal / pathological

 

number of injections per day

number of injection (time-) points per day

 

type of treatment

pump y/n

 

daily insulin dose

Units per day

1 decimal

daily basal insulin

Units per day

1 decimal

daily prandial insulin

Units per day

1 decimal

sensor use

y/n, yes = on a regular base (> 80% of the days since last data entry)

 

type of basal insulin

only NPH, only analog, both

analog / normal

type of prandial insulin

only NI, only analog, both

 

oral antidiabetics

name of generic

 

injectable (non-insulin) antidiabetics

y/n

 

severe hypoglycémia

coma, seizure ; number since last data entry

 

DKA leading to hospitalisation

number since last data entry

 

screening of nephropathy

spoturine : value of albuminuria

OR

 

 

screening proceeded y/n

if yes then…

normal/pathologic

2 fields

screening of retinopathy

screening proceeded y/n

if yes then…

presence of retinopathy  yes / no (as minimal consent)

2 fields

last update on 11.11.2014

Type 3 Diabetes Subtypes and Diabetes associated syndromes pdf

Number

Diabetes Subtype

 

A. Genetic defects of β -cell function

1

Chromosome 12, HNF−1α (MODY3)

2

Chromosome 7, glucokinase (MODY2)

3

Chromosome 20, HNF−4α (MODY1)

4

Chromosome 13, insulin promoter factor- (IPF-1; MODY4)

5

Chromosome 17, HNF−1β (MODY5)

6

Chromosome 2, NeuroD1 (MODY6)

7

Mitochondrial DNA mutation

8

Chromosome 7, KCNJ11 (Kir6.2)

9

Others

 

B. Genetic defects in insulin action

10

1. Type A insulin resistance

12

2. Leprechaunism

13

3. Rabson-Mendenhall syndrome

14

4. Lipoatrophic diabetes

15

5. Others

 

C. Diseases of the exocrine pancreas

16

1. Pancreatitis

17

2. Trauma / pancreatectomy

18

3. Neoplasia

19

4. Cystic fibrosis

20

5. Haemochromatosis

21

6. Fibrocalculous pancreatopathy

22

7. Others

 

D. Endocrinopathies

23

1. Acromegaly

24

2. Cushing’s syndrome

25

3. Glucagonoma

26

4. Phaeochromocytoma

27

5. Hyperthyroidism

28

6. Somatostatinoma

29

7. Aldosteronoma

30

8. Others

 

E. Drug- or chemical-induced

31

1. Vacor

32

2. Pentamidine

33

3. Nicotinic acid

34

4. Glucocorticoids

35

5. Thyroid hormone

36

6. Diazoxide

37

7. β-adrenergic agonists

38

8. Thiazides

39

9. Dilantin

40

10. α -Interferon

41

11. Others

 

F. Infections

42

1. Congenital rubella

43

2. Cytomegalovirus

44

3. Rabson-Mendenhall syndrome

 

G. Uncommon forms of immune-mediated diabetes

45

1. ‘‘Stiff-man’’ syndrome

46

2. Anti-insulin receptor antibodies

47

3. Others

48

4. Polyendocrine autoimmune deficiencies APS I and II

 

H. Other genetic syndromes sometimes associated with diabetes

49

1. Down syndrome

50

2. Klinefelter syndrome

51

3. Turner syndrome

52

4. Wolfram syndrome

53

5. Friedreich’s ataxia

54

6. Huntington’s chorea

55

7. Laurence-Moon-Biedl syndrome

56

8. Myotonic dystrophy

57

9. Porphyria

58

10. Prader-Willi syndrome

59

11. Others

 last update on 11.11.2014